Your Daily Pharma Scoop: Epizyme Down, MiMedx Proceeds, Summit Beats [Seeking Alpha]
Epizyme, Inc. (EPZM)
Last epizyme, inc. earnings: 2/24 06:30 am
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epizyme.com
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Source: Seeking Alpha
Summary Stocks in News: EPZM, MDXG Epizyme down 8% premarket on termination of tazemetostat in DLBCL & delay in NDA filing for ES Discussion : Epizyme ( EPZM ) announced the termination of the development program of tazemetostat in diffuse large B-cell lymphoma (‘DLBCL). Main reason for the abandonment is the lack of statistically significant efficacy data and the extended timeline for the filing of its NDA for epithelioid sarcoma (‘ES). The company plans to include more mature durability data into its NDA for tazemetostat in ES. Accordingly the timeline for such inclusion and submission is now extended to H1 2019. The market responded negatively to the news by pushing the share price 8% down. Company’s decision to abandon the development plan of tazemetostat for DLBCL is directly related to the company’s effort to focus on the measures for lifting the FDA's partial clinical hold on tazemetostat trials. After a pediatric patient developed secondary lymphoma, the trial
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