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0 -0.00201342281879202 0.00219239373601775 -0.00219239373601795 0.00223713646532434 -0.00756152125279648 -0.0111856823266221 -0.00223713646532454
Stock impact report

Equillium spikes 22% after early Phase 2 data for lupus nephritis candidate [Seeking Alpha]

Equillium, Inc. (EQ) 
Last equillium, inc. earnings: 3/26 04:07 pm Check Earnings Report
Company Research Source: Seeking Alpha
Equillium spikes 22% after early Phase 2 data for lupus nephritis candidateSep. 27, 2022 10:20 AM ETEquillium, Inc. (EQ)By:Dulan LokuwithanaSA News EditorBeritKNASDAQ:added ~22% ilead asset itolizumab in lupus nephritis (LN).The ongoing second portion of the Phase 1b trial is designed to test the subcutaneous delivery of 1.6 mg/kg itolizumab every two weeks over 24 weeks in up to 20 patients.Highlights of the results indicate 3 of 6 (50%) subjects achieved Complete Response (CR) by week 28, while 2 of 6 (33%) subjects reached partial response (PR), including 4 of 6 (67%) of those who indicated more than 80% decline in urine protein creatinine ratio (UPCR).In those subjects who received more than one dose, the average UPCR decline stood at 60%, while 8 of 12 (67%) showed an over 50% reduction in UPCR. The data were based on patients with high proteinuria.The drug was found to be safe and well tolerated in general, with no drug-related serious adverse events. Further data from thestudy Show less Read more
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