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0.01114511160463 0.0131919640572709 0.00193427556774574 -0.0343154813685256 -0.0236513800902662 -0.0436081915035155 -0.0364442079192721 -0.0594712980114828
Stock impact report

Erasca stock sinks 50% after patient death in drug trial [Yahoo! Finance]

Erasca, Inc. (ERAS) 
Company Research Source: Yahoo! Finance
About a month into treatment with ERAS-0015, Erasca's experimental pan-RAS molecular glue, the 66-year-old man — who had metastatic pancreatic cancer — was hospitalized with grade 3 pneumonitis, a serious form of lung inflammation. Doctors halted the drug and initiated aggressive treatment including high-dose steroids, but the patient ultimately decided to discontinue supportive care, and he died. During a call with analysts on Monday evening, Lim said the investigator believed the outcome might have been different if the patient had continued supportive care. He explained that pneumonitis is rare in many cancer treatments and that, before this case, ERAS-0015 had not caused any grade 4 or grade 5 events. The fatality reached that level only because the patient chose to stop care. The death occurred as the trial also showed promising results . For patients with KRAS G12X-mutated non-small cell lung cancer who received ERAS-0015 as a second-line treatment, 62% responded. In patien Show less Read more
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