Esperion Nominates ESP-2001 as Preclinical Development Candidate for Treatment of Primary Sclerosing Cholangitis
Esperion Therapeutics, Inc. (ESPR)
Last esperion therapeutics, inc. earnings: 2/27 07:00 am
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Source: GlobeNewswire
– Highly-Specific Allosteric ACLY Inhibitor Designed to Target Liver and Bile Duct Injury, Inflammation, and Fibrosis Associated with Primary Sclerosing Cholangitis (PSC) and Related Diseases – – ESP-2001 Has the Potential to Meaningfully Impact the Progression of PSC, a Disease with No Approved Treatments – ANN ARBOR, Mich., Oct. 16, 2025 (GLOBE NEWSWIRE) -- Esperion (NASDAQ: ESPR) today announced the nomination of ESP-2001, the Company’s highly-specific allosteric ATP citrate lyase (ACLY) inhibitor, as preclinical development candidate for the treatment of primary sclerosing cholangitis (PSC). With this candidate selection, the Company will begin Investigational New Drug (IND)-enabling studies with a goal to file an IND with the U.S. Food and Drug Administration (FDA) to initiate first-in-human clinical studies in 2026. “The nomination of ESP-2001 marks a pivotal moment in Esperion’s evolution as we expand our therapeutic focus beyond cardiovascular disease,” said Sheldon Koeni
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News
- Esperion Therapeutics (NASDAQ:ESPR) was upgraded by analysts at Piper Sandler to a "strong-buy" rating.MarketBeat
- Esperion Therapeutics (NASDAQ:ESPR) is now covered by analysts at Piper Sandler. They set an "overweight" rating and a $9.00 price target on the stock.MarketBeat
- Why Analysts Are Rewriting Esperion's Story After New Pipeline Results and Global Partnerships [Yahoo! Finance]Yahoo! Finance
- Esperion Partner Otsuka Launches NEXLETOL® in Japan for the Treatment of HypercholesterolemiaGlobeNewswire
- Esperion to Participate in Piper Sandler 37th Annual Healthcare ConferenceGlobeNewswire
ESPR
Earnings
- 11/6/25 - Miss
ESPR
Sec Filings
- 11/17/25 - Form 3
- 11/14/25 - Form SCHEDULE
- 11/12/25 - Form SCHEDULE
- ESPR's page on the SEC website