Edgewise Therapeutics Doses First Patient in Phase 2 CIRRUS-HCM Trial of EDG-7500 in Obstructive Hypertrophic Cardiomyopathy (HCM) [Yahoo! Finance]
Edgewise Therapeutics, Inc. (EWTX)
Company Research
Source: Yahoo! Finance
announced the dosing of the first patient in the Phase 2 CIRRUS-HCM trial of EDG-7500. EDG-7500 is a novel oral, selective, cardiac sarcomere modulator, specifically designed to slow early contraction velocity and address impaired cardiac relaxation associated with HCM and other diseases of diastolic dysfunction. The Phase 2 trial will assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics of EDG-7500 in patients with obstructive HCM. Part A of the trial will evaluate single doses and Part B will evaluate multiple oral doses of EDG-7500 over 28 days. "Based on the strength of clinical and preclinical data to-date, we are advancing EDG-7500 into the Phase 2 CIRRUS-HCM trial in patients with obstructive HCM," said Marc Semigran, M.D., Chief Development Officer, Edgewise Therapeutics. "We are encouraged by the effects of EDG-7500 observed in a translatable preclinical disease model of obstructive HCM. EDG-7500 demonstrated potent left ventricular (LV) outflow tract
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News
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- Edgewise Therapeutics to Present at the RBC Capital Markets Global Healthcare Conference on May 15, 2024 [Yahoo! Finance]Yahoo! Finance
- Edgewise Therapeutics to Present at the RBC Capital Markets Global Healthcare Conference on May 15, 2024Business Wire
- Edgewise Therapeutics Reports First Quarter 2024 Financial Results and Recent Business Highlights [Yahoo! Finance]Yahoo! Finance
- Edgewise Therapeutics Reports First Quarter 2024 Financial Results and Recent Business HighlightsBusiness Wire
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- 5/9/24 - Beat
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Sec Filings
- 5/10/24 - Form 8-K
- 5/10/24 - Form S-3ASR
- 5/9/24 - Form S-8
- EWTX's page on the SEC website