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Stock impact report

Exelixis and Natera to Collaborate on STELLAR-316, a Phase 3 Pivotal Trial of Zanzalintinib for Patients with Colorectal Cancer [Yahoo! Finance]

Exelixis, Inc. (EXEL) 
Last exelixis, inc. earnings: 2/25 04:05 pm Check Earnings Report
Company Research Source: Yahoo! Finance
ALAMEDA, Calif. & AUSTIN, Texas, January 07, 2026 BUSINESS WIRE Exelixis, Inc. (Nasdaq: EXEL) and Natera (Nasdaq: NTRA), a global leader in cell-free DNA and precision medicine, today announced their collaboration on the planned Exelixis-sponsored STELLAR-316 trial. This randomized phase 3 pivotal trial will evaluate zanzalintinib, Exelixis' novel oral kinase inhibitor, with and without an immune checkpoint inhibitor, in patients with resected stage II/III colorectal cancer (CRC). Using Natera's Signatera™ test following completion of definitive therapy*, patients with CRC who test positive for molecular residual disease (MRD) and have no radiographic evidence of disease will be eligible for enrollment in the STELLAR-316 trial. Working with patients and their providers, this trial will be fully enrolled with patients who are receiving commercial Signatera testing as part of their routine standard of care. The primary endpoint of STELLAR-316 is disease-free survival. Signatera wil Show less Read more
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