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-0.00116009280742447 -0.00116009280742447 -0.00116009280742447 0.00977958236658929 -0.00116009280742463 0.0406032482598608 0.0406032482598608 0.0406032482598608
Stock impact report

Obsidian, Galera to advance cell therapy following reverse merger [Yahoo! Finance]

GALERA THERAPEUTICS INC (GRTX) 
Company Research Source: Yahoo! Finance
Obsidian Therapeutics, a private biotechnology company, will begin trading on the Nasdaq following a reverse merger with Galera Therapeutics announced Tuesday. The combined company will focus on developing Obsidian's main asset, a cell therapy codenamed OBX-115. The medicine is created using white blood cells known as tumor infiltrating lymphocytes, or TILs, that are harvested from the patient, engineered to better fight cancer and then reinfused. In 2024, Iovance Biotherapeutics' Amtagvi became the first TIL cell therapy approved by the Food and Drug Administration. OBX-115 is currently in human testing, where researchers are evaluating it in a mid-stage trial for advanced melanoma and an early-stage study for non-small cell lung cancer. The therapy, according to Obsidian, is designed to be durable as well as easier on the patient in several ways. For example, it doesn't require patients to take “interleukin-2” drugs, which are highly toxic but often useful for supporting the tr Show less Read more
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