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G1 Therapeutics Presents Phase 1b Data on G1T38 in Combination with Faslodex for Treatment of Breast Cancer at 2018 American Society of Clinical Oncology (ASCO) Annual Meeting

G1 Therapeutics, Inc. (GTHX) 
Last g1 therapeutics, inc. earnings: 2/26 04:01 pm Check Earnings Report
Company Research Source: GlobeNewswire
RESEARCH TRIANGLE PARK, N.C., June 02, 2018 (GLOBE NEWSWIRE) -- G1 Therapeutics, Inc. (Nasdaq:GTHX), a clinical-stage oncology company, today announced that preliminary data from its Phase 1b/2a clinical trial of G1T38 in combination with Faslodex® (fulvestrant) showed promising safety, tolerability and efficacy when G1T38 was dosed continuously as a treatment for people with estrogen receptor-positive, HER2-negative (ER+, HER2-) breast cancer. These data were presented today in a poster session at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting. G1T38 is an oral CDK4/6 inhibitor with broad therapeutic potential in many forms of cancer and may serve as backbone therapy for multiple combination regimens. “The findings in this trial support continuous daily dosing of G1T38. Neutrophil declines are an important marker of effective CDK4/6 inhibition and tumor arrest, but excessive declines can result in severe neutropenia. All G1T38 dose levels studied in this Show less Read more
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