Fractyl Health Announces New Results From Its Rejuva® Platform Demonstrating Potent and Durable Effects of a Single Dose of a Human GLP-1 Pancreatic Gene Therapy Transgene Compared to Sema...
Fractyl Health, Inc. (GUTS)
Company Research
Source: Yahoo! Fi
The human GLP-1 transgene sequence used in RJVA-001 was administered to eight-week-old db/db mice with established disease and resulted in up to 50% blood sugar lowering and 11% weight loss vs vehicle at four weeks after a single administration, compared to 32% glucose lowering and 2% weight loss vs vehicle with chronic semaglutide. These results with a native, short half-life human GLP-1 sequence to be used in RJVA-001 build upon earlier results with a prototype transgene GLP-1 analogue. BURLINGTON, Mass., March 12, 2024 (GLOBE NEWSWIRE) -- Fractyl Health, Inc. (Nasdaq: GUTS) (the “Company”), a metabolic therapeutics company focused on pioneering new approaches for the treatment of obesity and type 2 diabetes (T2D), today announced promising new preclinical findings for the first clinical candidate in its Rejuva ® pancreatic gene therapy platform. RJVA-001 is the Company's first GLP-1 gene therapy candidate to emerge from the platform, setting the stage for a potentially transfo
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News
- Fractyl Health to Present at BofA Securities 2024 Health Care Conference [Yahoo! Finance]Yahoo! Finance
- Fractyl Health to Present at BofA Securities 2024 Health Care ConferenceGlobeNewswire
- Fractyl Health to Report First Quarter 2024 Financial Results and Provide Business Updates on May 13, 2024 [Yahoo! Finance]Yahoo! Finance
- Fractyl Health to Report First Quarter 2024 Financial Results and Provide Business Updates on May 13, 2024GlobeNewswire
- Fractyl Health, Inc.'s (NASDAQ:GUTS) largest shareholders are private equity firms with 52% ownership, individual investors own 30% [Yahoo! Finance]Yahoo! Finance
GUTS
Sec Filings
- 4/2/24 - Form 4
- 4/2/24 - Form 3
- 4/1/24 - Form 10-K
- GUTS's page on the SEC website