Fractyl Health's REVEAL-1 Study Shows Positive Six-Month Results for Revita in Maintaining Weight and Glycemic Control Post-GLP-1 Use [Yahoo! Finance]
Fractyl Health, Inc. (GUTS)
Company Research
Source: Yahoo! Finance
positive six-month results from its open-label REVEAL-1 study. The data showed that a single Revita procedure, a hydrothermal ablation designed to remodel the duodenal lining, successfully maintained stable body weight and glycemic control in patients who had recently discontinued GLP-1 medications. Participants in the study had previously lost an average of 24% of their total body weight (over 50 lbs.) while on GLP-1 therapy for durations ranging from 5 months to 5 years. The findings are significant when compared to typical outcomes following the withdrawal of GLP-1 drugs. While published third-party studies show a weight regain of ~10% within 6 months of stopping medication, Revita-treated participants showed a mean weight change of only 1.5%. Furthermore, metabolic stability was mirrored in blood sugar levels; while historical data from the STEP-1 trial indicated a 0.4% increase in HbA1c post-discontinuation, REVEAL-1 participants experienced a minimal change of only 0.04%.
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News
- Fractyl Health Appoints Lara Smith Weber as Chief Financial Officer to Support Commercial-Stage PreparednessGlobeNewswire
- Fractyl Health Enters a Catalyst-Rich 2026 Positioned to Define the Post-GLP-1 Weight Maintenance Therapeutic Category [Yahoo! Finance]Yahoo! Finance
- Fractyl Health Enters a Catalyst-Rich 2026 Positioned to Define the Post-GLP-1 Weight Maintenance Therapeutic CategoryGlobeNewswire
- Analysts Keep Buy Ratings on Fractyl Health (GUTS) [Yahoo! Finance]Yahoo! Finance
- Fractyl Health (NASDAQ:GUTS) had its "buy" rating reaffirmed by analysts at Canaccord Genuity Group Inc..MarketBeat
GUTS
Earnings
- 3/3/25 - Miss
GUTS
Sec Filings
- 1/6/26 - Form 8-K
- 1/5/26 - Form 8-K
- 12/17/25 - Form 4
- GUTS's page on the SEC website