Hoth Therapeutics (HOTH) Reports Positive HT-VA CRADA Data: GDNF Reprograms Liver Fat Metabolism, Shuts Down Fat-Creation Gene and Activates Fat-Burning Pathways, Outperforming Semaglutide...
Hoth Therapeutics, Inc. (HOTH)
Company Research
Source: Yahoo! Finance
NEW YORK April 13, 2026 /PRNewswire/ -- Hoth Therapeutics, Inc. (NASDAQ: HOTH) , a clinical-stage biopharmaceutical company, today announced positive data from its HT-VA study, conducted under its Cooperative Research and Development Agreement (CRADA) with the U.S. Department of Veterans Affairs and Emory University, demonstrating that parenteral GDNF (Glial Cell-Derived Neurotrophic Factor) directly reprograms liver fat metabolism at the genetic level in a preclinical model of metabolic-associated fatty liver disease (MAFLD). (PRNewsfoto/Hoth Therapeutics Inc.) The data highlights statistically significant improvements in key genes responsible for fat production and fat metabolism, positioning GDNF as a potentially differentiated therapeutic approach targeting the root cause of fatty liver disease and metabolic dysfunction. Statistically significant reduction in Srebf1, a key gene driving fat production in the liver Increased expression of Ppara, a central regulator of fat m
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HOTH
News
- Rewriting Fat Itself: Hoth Therapeutics May Be Targeting the Root of Metabolic Disease [TheStreet.com]TheStreet.com
- Hoth Therapeutics (HOTH) Reports Positive HT-VA CRADA Data: GDNF Reprograms Liver Fat Metabolism, Shuts Down Fat-Creation Gene and Activates Fat-Burning Pathways, Outperforming SemaglutidePR Newswire
- Hoth Therapeutics (HOTH) Reports Positive HT-VA CRADA Data: GDNF Reprograms Liver Fat Metabolism, Shuts Down Fat-Creation Gene and Activates Fat-Burning Pathways, Outperforming Semaglutide [TheStreet.com]TheStreet.com
- Hoth Therapeutics (HOTH) Reports Positive HT-VA CRADA Data: GDNF Reprograms Liver Fat Metabolism, Shuts Down Fat-Creation Gene and Activates Fat-Burning Pathways, Outperforming SemaglutidePR Newswire
- Hoth Therapeutics Announces Closing of $2.0 Million Registered Direct OfferingPR Newswire
HOTH
Sec Filings
- 4/16/26 - Form 8-K
- 4/16/26 - Form 424B5
- 4/2/26 - Form 8-K
- HOTH's page on the SEC website