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Stock impact report

ImmunityBio's (IBRX) ANKTIVA Shows Survival Gains in Lung Cancer Patients [Yahoo! Finance]

ImmunityBio, Inc. (IBRX) 
Company Research Source: Yahoo! Finance
promising Phase 2 QUILT-3.055 trial results at the IASLC World Conference on Lung Cancer, showing that ANKTIVA significantly reverses lymphopenia in advanced NSCLC patients resistant to checkpoint inhibitors. ImmunityBio's (IBRX) ANKTIVA Shows Survival Gains in Lung Cancer Patients Pressmaster/Shutterstock.com This immune restoration translated into prolonged median overall survival (mOS), with patients maintaining higher lymphocyte counts living up to 21.1 months. The therapy is being further evaluated in the Phase 3 ResQ201A trial alongside checkpoint inhibitor tislelizumab. ANKTIVA, a first-in-class IL-15 agonist fusion complex, activates NK and T cells depleted by standard cancer treatments. It mimics natural IL-15 receptor biology to restore immune memory and overcome tumor resistance. In the trial, 80% of patients exceeded an ALC of 1,200 cells/µL, with mOS of 15.8 months compared to 11.5 months in those who did not. These findings support ANKTIVA's role as a lymphoresto Show less Read more
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