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0 0.00389863547758294 0.000350877192982504 0.000350877192982504 -0.0148148148148147 0.00584795321637432 0 -0.0279922027290447
Stock impact report

ImmunityBio immunotherapy shows positive overall survival in lung cancer trial [Seeking Alpha]

ImmunityBio, Inc. (IBRX) 
Company Research Source: Seeking Alpha
trial evaluating its immunotherapy drug, Anktiva, in non-small cell lung cancer (NSCLC). The QUILT 3.055 trial included 2nd- and 3rd-line NSCLC patients whose disease progressed after checkpoint inhibitor therapy (pembrolizumab, nivolumab, or atezolizumab) and standard-of-care chemotherapy. In NSCLC patients who relapsed or were refractory to checkpoint inhibitors, Anktiva was administered together with the same checkpoint inhibitor. The addition of Anktiva resulted in the rescue of the checkpoint therapy efficacy, with significant prolongation of overall survival. Positive results were seen in both PD-L1 negative and PD-L1 positive participants with NSCLC. Anktiva, an IL-15 agonist immunotherapy, works by activating the body's natural killer cells and killer T-cell immune system to attack tumor cells. “Data reaffirms the mechanism of action of Anktiva as an immune cell enhancer that activates natural killer cells and memory T cells to rescue checkpoint inhibitor failures acro Show less Read more
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