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0.00241351568785206 -0.00402252614641987 -0.0104585679806918 0.000804505229283973 0.00563153660498796 -0.00241351568785192 0.00896218825422377 0.0090104585679807
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ImmunityBio Launches Phase 2 Chemotherapy-Free CAR-NK Cell Therapy Trial with ANKTIVA® (ResQ215B) in Indolent Lymphomas

ImmunityBio, Inc. (IBRX) 
Company Research Source: Business Wire
First Phase 2 chemotherapy-free, lymphodepletion-free, off-the-shelf CAR-NK cell therapy plus ANKTIVA® and rituximab regimen to be evaluated in indolent non-Hodgkin lymphoma (iNHL), including Waldenström’s MacroglobulinemiaResQ215B builds on a Phase 1 study that demonstrated that CAR-NK cell therapy plus rituximab administered without chemotherapy or ANKTIVA in iNHL, including Waldenström’s Macroglobulinemia, resulted in durable complete responsesCD19 t-haNK, an off-the-shelf CAR-NK cell therapy, is designed to induce direct tumor cell killing and enhance antibody-dependent cellular cytotoxicity (ADCC) when combined with anti-CD20 antibody rituximabThe addition of ANKTIVA aims to further enhance NK and T-cell activity and potentially overcome tumor resistance to rituximab, thereby improving the depth and durability of responses in indolent lymphomas CULVER CITY, Calif.--(BUSINESS WIRE)--ImmunityBio, Inc. (NASDAQ: IBRX), a commercial-stage immunotherapy company, today announced the Show less Read more
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