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0.00135869565217388 0.00135869565217388 0.016304347826087 0.0135869565217391 -0.00815217391304355 -0.00815217391304342 -0.0421195652173912 -0.0381114130434783
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ImmunityBio Reports Median Overall Survival Not Yet Reached and Lymphopenia Reversed in Recurrent Glioblastoma Patients Receiving ANKTIVA® Plus CAR-NK, Chemo-Free Therapy

ImmunityBio, Inc. (IBRX) 
Company Research Source: Business Wire
Primary endpoint of QUILT-3.078 is overall survival; median overall survival has not yet been reached, with 19 of 23 enrolled patients alive as of January 22, 2026Fourteen patients have evaluable data, with the longest survival from time of disease recurrence reaching 12 months to date and ongoingBaseline mean absolute lymphocyte count (ALC) among these 14 patients was 0.9 x 103/uL, confirming severe lymphopenia at enrollmentALC increased within one treatment cycle, with mean ALC rising to = 1.4 x 103/uL (p Immune competence (as measured by ALC) was maintained, with statistically significant increases from baseline observed at all assessments through 20 weeks (p = 0.026) with ANKTIVA® + CAR-NKANKTIVA + CAR-NK demonstrated a manageable safety profile following a total of 219 doses administered to date, with three treatment-related serious adverse events reported among 41 GBM patients (2L and 3L+) enrolled across QUILT-3.078 (N=23) and single-patient INDs (N=18)Randomized controlled tri Show less Read more
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