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0.0011682242990654 0 -0.0011682242990654 0 0.00350467289719619 0.00459112149532719 -0.00112149532710268 -0.00221962616822431
Stock impact report

ImmunityBio (IBRX) Resubmits sBLA to FDA for ANKTIVA in Papillary Bladder Cancer [Yahoo! Finance]

ImmunityBio, Inc. (IBRX) 
Company Research Source: Yahoo! Finance
highest upside potential . On March 9, ImmunityBio announced the resubmission of its sBLA to the FDA for ANKTIVA in combination with Bacillus Calmette-Guérin/BCG. This filing specifically targets patients with BCG-unresponsive non-muscle invasive bladder cancer/NMIBC who present with papillary disease. The resubmission follows an initial review in early 2026, during which the FDA requested additional long-term efficacy and follow-up data to support the treatment's potential in this specific patient population. The sBLA is supported by results from the QUILT 3.032 Phase 2/3 trial, which showed durable outcomes for patients with high-grade papillary-only disease. Data published in The Journal of Urology showed a 12-month disease-free survival rate of 58.2% and a bladder preservation rate of 81.8% at 36 months. These findings highlight ANKTIVA's role as an IL-15 superagonist that activates natural killer and killer T cells to prevent progression to muscle-invasive disease without the n Show less Read more
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