Idera Pharmaceuticals Announces Immuno-Oncology Clinical Research Collaboration with AbbVie
Idera Pharmaceuticals, Inc. (IDRA)
Last idera pharmaceuticals, inc. earnings: 11/6 04:01 pm
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Source: GlobeNewswire
EXTON, Pa., Sept. 04, 2019 (GLOBE NEWSWIRE) -- Idera Pharmaceuticals, Inc. (NASDAQ: IDRA) announced today that they have entered into an immuno-oncology clinical research collaboration with AbbVie, a global, research-based biopharmaceutical company. The purpose of the collaboration is to conduct a clinical study evaluating whether combinations of an OX40 agonist (ABBV-368), a TLR-9 agonist (tilsotolimod), chemotherapy (nab-paclitaxel) and/or an anti-programmed cell death 1 (PD-1) antagonist (ABBV-181) stimulate the immune system resulting in anti-tumor responses. This Phase 1b, multi-center, open-label study is designed to determine the safety, tolerability, pharmacokinetics and preliminary efficacy of combinations of ABBV-368 plus tilsotolimod in subjects with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC). The study will test three separate treatment arms: ABBV-368 plus tilsotolimod;ABBV-368 plus tilsotolimod and nab-paclitaxel; andABBV-368 plus tilsotol
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