InflaRx Reports New Mechanistic Data for Izicopan Supporting its Potential as a Best-in-Class C5aR Inhibitor
InflaRx N.V. (IFRX)
Last inflarx n.v. earnings: 8/14 04:05 pm
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US:NASDAQ Investor Relations:
inflarx.com/home/investors/press-releases/01-2018--inflarx-to-present-at-upcoming-investor-conferences.html
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Source: GlobeNewswire
JENA, Germany, April 09, 2026 (GLOBE NEWSWIRE) -- InflaRx N.V. (Nasdaq: IFRX), a biopharmaceutical company pioneering anti-inflammatory therapeutics by targeting the complement system, today announced new in vitro findings demonstrating that izicopan does not exhibit time-dependent inhibition of CYP3A4, an important indicator for the risk for drug-drug interactions (DDIs) and liver toxicity. These results further support izicopan’s potential as a differentiated, best-in-class oral C5a receptor (C5aR) inhibitor. To build upon previous CYP interaction data for izicopan, which showed only marginal inhibition of CYP3A4 (IC50 = 62 µM) in a time-dependent inhibition (TDI) IC50 shift assay, InflaRx conducted a mechanistically informative Ki-based TDI (Ki/Kinact) study. While TDI shift assays serve as rapid screening tools to identify potential time-dependent inhibition, Ki/Kinact studies provide a more definitive and quantitative assessment, enabling a reliable determination of the presen
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News
- InflaRx Announces Participation in the Raymond James 2026 Biotech Innovation SymposiumGlobeNewswire
- InflaRx Highlights Clinical Activity of Vilobelimab in Pyoderma Gangrenosum in Late-Breaker Oral Presentation at 2026 American Academy of Dermatology Annual MeetingGlobeNewswire
- InflaRx (IFRX) had its price target lowered by Guggenheim from $22.00 to $14.00. They now have a "buy" rating on the stock.MarketBeat
- InflaRx Reports Full Year 2025 Results and Highlights Key Achievements and Expected MilestonesGlobeNewswire
- InflaRx Announces Late-Breaker Oral Presentation on Vilobelimab Phase 3 Results in Pyoderma Gangrenosum at 2026 American Academy of Dermatology Annual MeetingGlobeNewswire
IFRX
Earnings
- 3/19/26 - Miss
IFRX
Sec Filings
- 4/9/26 - Form 6-K
- 4/2/26 - Form 6-K
- 3/20/26 - Form 20-F
- IFRX's page on the SEC website