Inmagene Reports Topline Results from Phase 2a Study of IMG-007, a Nondepleting Anti-OX40 Monoclonal Antibody with an Extended Half-life, in Patients with Alopecia Areata [Yahoo! Finance]
Ikena Oncology, Inc. (IKNA)
Company Research
Source: Yahoo! Finance
Patients in Cohort 2 showed a sustained improvement in Severity of Alopecia Tool (SALT) score, which did not plateau by Week 36, approximately eight months after the last dose: The mean reduction in SALT score at Week 36 was 21.7% in patients with baseline SALT score of 50 to 100, and 30.1% in the subset of patients with baseline SALT score of 50 to A durable inhibition of inflammatory markers of T helper (Th)1, Th2 and CD8+ T cells were observed at Week 16, approximately three months after the last dose IMG-007 was overall well-tolerated with no reports of pyrexia or chills SAN DIEGO, April 24, 2025 (GLOBE NEWSWIRE) -- Inmagene Biopharmaceuticals (“Inmagene” or the “Company”), a clinical-stage biotechnology company focused on developing innovative and differentiated therapies for immunological and inflammatory (“I&I”) diseases, today reports topline results from the Phase 2a trial of IMG-007 in patients with severe alopecia areata (“AA”). “AA is an I&I disease with tremen
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