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Stock impact report

JPM26: Immunocore Signals Entry into Type 1 Diabetes [Yahoo! Finance]

Immunocore Holdings plc - American Depositary Shares (IMCR) 
Company Research Source: Yahoo! Finance
its ImmTAX TCR-bispecific platform beyond oncology and infectious disease into autoimmune conditions, including type 1 diabetes (T1D). The company plans to dose the first patient in a Phase I trial of IMC S118AI, an ImmTAAI (Immune mobilising monoclonal TCRs Against AutoImmune disease) candidate targeting T1D, in the first half of 2026, with a second autoimmune asset, IMC U120AI for inflammatory dermatology, expected to enter the clinic in the second half of the year. This announcement marks Immunocore's formal move into disease-modifying T1D immunotherapy and positions its TCR-based approach as a potential future competitor to existing and emerging immune intervention strategies. T1D is a chronic, immune-mediated disease characterised by T cell–driven destruction of insulin-producing pancreatic beta cells, leading to absolute insulin deficiency and lifelong dependence on exogenous insulin. The disease typically presents in childhood or adolescence but can occur at any age, and is a Show less Read more
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