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Stock impact report

Immunome: Upcoming NDA, Valuation, And Investment Case [Seeking Alpha]

Immunome, Inc. (IMNM) 
Company Research Source: Seeking Alpha
Varegacestat demonstrated superior efficacy and safety versus nirogacestat, with an 84% risk reduction in progression or death and a 56% objective response rate. Despite a small addressable market (~3,000 patients), conservative peak global sales are estimated at $280 million, supporting a valuation over 235% above IMNM's current market cap. I view IMNM as a cautious buy ahead of regulatory catalysts, but risks include market size, competition from big pharma, and limited pipeline depth. The Good Brigade/DigitalVision via Getty Images Immunome ( IMNM ) will be submitting an NDA for its lead drug candidate, varegacestat, in Q2 2026. Varegacestat aims to treat desmoid tumors, a rare, aggressive soft tissue tumor with limited treatment options. IMNM recently This article was written by Analyst's Disclosure: I/we have no stock, option or similar derivative position in any of the companies mentioned, and no plans to initiate any such positions within the next 72 hours. I wrote Show less Read more
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