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Stock impact report

IMNN: OVATION 2 Translational Data Shows IMNN-001 Alters Tumor Microenvironment… [Yahoo! Finance]

Imunon, Inc. (IMNN) 
Company Research Source: Yahoo! Finance
Translational Data from OVATION 2 Trial Presented at AACR Special Conference On September 22, 2025, Imunon, Inc. (NASDAQ:IMNN) announced that new translational data from the Phase 2 OVATION 2 trial of IMNN-001 was presented at the American Association for Cancer Research (AACR) Special Conference in Cancer Research: Advances in Ovarian Cancer Research. The poster can be found here The data consisted of an analysis of immune markers expression (CD8, CD11c, CD44, CD4, HLA-DR, CD45, CD45RO, Ki67, CD14, CD3, CD20, CD56, HLA-A, CD68, CD163, CD11b, CD16, Pan CK, FOXP3, PD-L1, PD-1, and IDO-1) in tumor samples from patients before and after treatment with IMNN-001. The following figure gives normalized changes in cell density for a subset of patients. The first row shows a favorable shift in the TME to immune stimulatory T cell ratios in the majority of patients, as exhibited by higher CD8+/Treg, CD8+/IDO+, and CD8+/CD4+ ratios. The second row shows a trend in favor of decreased immunos Show less Read more
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