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Immune Pharmaceuticals Announces Positive Preclinical Results in Asthma

IMMUNE PHARMACEUTICALS INC NE (IMNP) 
US:NASDAQ Investor Relations: immunepharma.com/investor-relations
Company Research Source: GlobeNewswire
A broad anti-inflammatory effect observed FORT LEE, N.J., Oct. 17, 2018 (GLOBE NEWSWIRE) -- Immune Pharmaceuticals, Inc. (OTCQB: IMNP) (“Immune” or the “Company”), a biopharmaceutical company developing novel therapeutic agents for the treatment of immunologic and inflammatory diseases, announced today positive results from a mouse study demonstrating that blockade of eotaxin-1 reduces lung inflammation and has a broader inhibitory effect on inflammatory cells than does blockade of interleukin (IL)-5. In a moue model of asthma, a monoclonal antibody to mouse eotaxin-1 reduced inflammatory cells counts in bronchoalveolar lavage (BAL) fluid from mice sensitized to house dust mite (HDM) allergen.  Eotaxin-1 blockade had an unexpectedly broad effect on all inflammatory cells, including not only eosinophils, but neutrophils, macrophages and lymphocytes as well.  In contrast, a monoclonal antibody to IL-5 produced a decline in eosinophils, but substantial increases in all other infl Show less Read more
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