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Inhibrx Biosciences Highlights 20% ORR for Ozekibart Combo in Late-Line Colorectal Cancer [Yahoo! Finance]

Inhibrx Biosciences, Inc. (INBX) 
Company Research Source: Yahoo! Finance
Phase I/II data evaluating ozekibart in combination with FOLFIRI in a heavily pretreated population that company executives said has historically seen minimal benefit from standard options. Late-line colorectal cancer data and patient population Founder and CEO Mark Lappe said the company's newly released results involved 45 evaluable patients with advanced or metastatic unresectable colorectal cancer (CRC). According to Lappe, 70% of patients received ozekibart plus FOLFIRI as fourth-line therapy and 30% received it as third-line therapy. He added that 80% of patients were already refractory to irinotecan. ? GE Vernova Beats Earnings by 790% as Data Center Demand Explodes Lappe contrasted the study outcomes with historical expectations in this setting, describing the standard of care as having an objective response rate (ORR) of “almost zero” and a median progression-free survival (PFS) of “only two to three months.” In the ozekibart combination cohort, Lappe reported an OR Show less Read more
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