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Stock impact report

GSK, Ionis claim study success for RNA-based hepatitis B drug [Yahoo! Finance]

Ionis Pharmaceuticals, Inc. (IONS) 
Last ionis pharmaceuticals, inc. earnings: 2/26 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: ionispharma.com
Company Research Source: Yahoo! Finance
GSK and Ionis Pharmaceuticals said their experimental hepatitis B medicine succeeded in two Phase 3 trials, offering patients what might be a “functional cure” for the disease. In releases issued Wednesday, the companies didn't provide details on the effects seen in the B-Well 1 and B-Well 2 studies. The drug, bepirovirsen, met the primary endpoint in both trials and “demonstrated a statistically significant and clinically meaningful functional cure rate,” the companies said. Global regulatory filings are planned for the first quarter of this year based on the data, the companies said. Researchers plan to release the full results at a future medical meeting and in a peer-reviewed journal. Health officials estimate that more than 2 billion people around the world have been infected with the hepatitis B virus and almost 300 million of those patients have developed chronic infections that can lead to cirrhosis and liver cancer. Infants exposed to the virus are especially at risk , Show less Read more
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