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0 0 0.00432472507104898 0.00432472507104898 0 0.00284196218954657 -0.00531323365871749 -0.00531323365871749
Stock impact report

Ionis Pharmaceuticals Inc (IONS) Q4 2025 Earnings Call Highlights: Strong Revenue Growth and ... [Yahoo! Finance]

Ionis Pharmaceuticals, Inc. (IONS) 
Last ionis pharmaceuticals, inc. earnings: 2/26 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: ionispharma.com
Company Research Source: Yahoo! Finance
This article first appeared on GuruFocus Revenue: $944 million in 2025, a 34% increase year-over-year. Commercial Products Revenue: $436 million, representing 46% of total revenue. R&D Collaborations Revenue: $508 million, representing 54% of total revenue. TRYNGOLZA Sales: $108 million in 2025, with $50 million in Q4, a 56% increase over Q3. DAWNZERA Sales: $8 million in 2025 from initial launch months. Royalty Revenues: Increased 11% to $285 million in 2025. Operating Expenses: Increased modestly year-over-year, driven by launch investments. Projected 2026 Revenue: $800 million to $825 million, a 20% increase over adjusted 2025 figures. Projected 2026 Operating Loss: Between $500 million and $550 million. Cash and Investments: Projected to end 2026 with approximately $1.6 billion. Warning! GuruFocus has detected 5 Warning Sign with IONS. Is IONS fairly valued? Test your thesis with our free DCF calculator. Release Date: February 25, 2026 For the complete Show less Read more
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