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0.00269070361899641 0.00295977398089599 0.00309430916184588 0.00349791470469535 0.00955199784743721 0.0146643347235302 0.0107628144759856 0.0119736311045338
Stock impact report

Ionis (IONS) Q4 2025 Earnings Transcript [Globe and Mail, The (Toronto, Canada)]

Ionis Pharmaceuticals, Inc. (IONS) 
Last ionis pharmaceuticals, inc. earnings: 2/26 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: ionispharma.com
Chief Development Officer — Holly Kordasiewicz Chief Commercial Officer — Kyle Jenne Chief Financial Officer — Elizabeth L. Hougen Chief Medical Officer — Eugene Schneider Executive Vice President, Research — Eric Swayze Need a quote from a Motley Fool analyst? Email pr@fool.com RISKS Elizabeth L. Hougen noted, "we expect a meaningful decline in TRYNGOLZA revenues throughout the year ahead of the sHTG launch," due to anticipated FCS revenue impacts prior to expansion. Guidance assumes standard FDA review timeline for olezarsen, limiting near-term sHTG revenue contributions if priority review is not granted. TAKEAWAYS Total revenue -- $944 million, a 34% increase year over year, driven by commercial product sales and R&D collaborations. Commercial product revenue -- $436 million, representing 46% of total revenue, with contributions from TRYNGOLZA and DAWNZERA. TRYNGOLZA sales -- $108 million for the year, including $50 million in the fourth quarter, a 56% quar Show less Read more
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