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0 -0.0361702127659574 -0.0404255319148937 0 -0.0829787234042552 -0.0148936170212767 -0.0148936170212767 0
Stock impact report

Inventiva announces positive results from the Phase II, LEGEND, Proof-of-Concept study combining lanifibranor with empagliflozin in patients with MASH/NASH and T2D [Yahoo! Finance]

Inventiva S.A. - American Depository Shares (IVA) 
Company Research Source: Yahoo! Finance
Statistical significance was also achieved on several markers of liver injury, markers of glucose and lipid metabolism, as well as hepatic steatosis. Patients treated with lanifibranor in combination with empagliflozin maintained a stable weight throughout the 24 weeks study, addressing the moderate, metabolically healthy, weight gain that has been observed in some patients treated with lanifibranor. Treatment with lanifibranor alone and in combination with empagliflozin decreased the ratio of visceral abdominal fat to subcutaneous fat, reflecting a shift from pro-inflammatory visceral fat towards metabolically healthy adipose tissue. The treatment with lanifibranor 800mg/once daily alone or in combination with empagliflozin for 24 weeks was well tolerated, with no safety concerns reported. Inventiva will host an investor webcast Tuesday, March 19 th at 8am ET (details below). Daix (France), Long Island City (New York, United States), March 18, 2024 – Inventiva (Euronext Pa Show less Read more
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