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Stock impact report

Inventiva drops after adverse event in Phase 3 trial for NASH drug [Seeking Alpha]

Inventiva S.A. - American Depository Shares (IVA) 
Company Research Source: Seeking Alpha
NASH, also known as nonalcoholic steatohepatitis, is characterized by the excessive accumulation of liver fat. An advanced form of nonalcoholic fatty liver disease, NASH represents a major unmet medical need with no FDA-approved therapies. The company made the announcement with its preliminary financials for 2023. Lanifibranor belongs to a drug class called peroxisome-activated receptor (PPAR) agonists. Other developers of liver-targeting PPAR agonists include Gilead's ( GILD new buyout target, CymaBay Therapeutics ( CBAY ), and Inventiva's ( IVA ) French rival, Genfit ( GNFT OTCPK:GNFTF Noting that the adverse event was treatment-related, Inventiva ( IVA ) has decided to discontinue lanifibranor therapy in the affected patient, whose subsequent findings indicated results compatible with autoimmune hepatitis. After reviewing the data, the trial's data monitoring committee has suggested modifications to the trial design. As a result, Inventiva ( IVA ) has decided to pause scre Show less Read more
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