Inventiva Phase 2 study for MASH drug meets primary endpoint [Seeking Alpha]
Inventiva S.A. - American Depository Shares (IVA)
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Source: Seeking Alpha
Lanifibranor was tested in combination with empagliflozin in patients with metabolic dysfunction-associated steatohepatitis, or MASH, also known as non-alcoholic steatohepatitis, or NASH, and type 2 diabetes. Empagliflozin is the generic name for Boehringer Ingelheim and Eli Lilly's ( LLY ) diabetes medication Jardiance. Inventiva said the Phase 2 proof-of-concept study met its primary endpoint with an absolute reduction of HbA1c of 1.14% to 1.59% in patients treated with lanifibranor or in combination with empagliflozin at week 24 versus an increase of 0.26% in the placebo arm. Patients treated with the combination also were able to maintain a stable weight throughout the 24 weeks of the study. Last week, Madrigal ( MDGL ) drug Rezdiffra became the first FDA-approved treatment for the liver disorder NASH. Several other companies are also working on therapies for NASH/MASH, including Lilly ( LLY ), Novo Nordisk ( NVO ), GSK ( GSK ), Viking Therapeutics ( VKTX ), Ascletis (
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News
- Non-Alcoholic Steatohepatitis (NASH) Pipeline Insight, 2024 Featuring 100+ Companies and 110+ Pipeline Drugs Including Lanifibranor (Inventiva Pharma), MSDC-0602K (Cirius Therapeutics), TERN-501 (Terns Pharma) [Yahoo! Finance]Yahoo! Finance
- Inventiva S.A. (NASDAQ: IVA) had its price target raised by analysts at Canaccord Genuity Group Inc. from $12.00 to $20.00. They now have a "buy" rating on the stock.MarketBeat
- Inventiva announces filing of its 2023 Universal Registration Document and 2023 Annual Report on Form 20-F [Yahoo! Finance]Yahoo! Finance
- Inventiva announces filing of its 2023 Universal Registration Document and 2023 Annual Report on Form 20-FGlobeNewswire
- Inventiva S.A. (NASDAQ:IVA) Q4 2023 Earnings Call Transcript [Yahoo! Finance]Yahoo! Finance
IVA
Sec Filings
- 5/3/24 - Form SC
- 4/3/24 - Form 20-F
- 3/27/24 - Form 6-K
- IVA's page on the SEC website