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Stock impact report

Inventiva resumes Phase 3 study for NASH drug, stock up 6% [Seeking Alpha]

Inventiva S.A. - American Depository Shares (IVA) 
Company Research Source: Seeking Alpha
Phase 3 study for its drug lanifibranor in the treatment of non-alcoholic steatohepatitis, or NASH. Inventiva had paused the trial in February after a patient suffered a suspected adverse reaction. The patient is expected to make a full recovery, the company said in a statement released late Thursday. The trial, called NATiV3, will now proceed with certain modifications, including liver monitoring every six weeks and the exclusion of newly screened patients diagnosed or with a predisposition to autoimmune liver and thyroid disease. Inventiva said screening and randomization have resumed at certain US sites and are expected to restart at other sites in the next few weeks. The last patient visit for the trial is targeted for the first half of 2024. Lanifibranor belongs to a class of drugs called PPAR agonists. Other companies developing liver-targeting PPAR agonists include Gilead Sciences ( GILD ), through its recently acquired Cymabay unit, and France's Genfit ( GNFT OTCPK:GNF Show less Read more
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