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Stock impact report

Invivyd (IVVD) Announces Favorable Phase 3 Analysis for VYD2311 COVID-19 Treatment [Yahoo! Finance]

Invivyd, Inc. (IVVD) 
Company Research Source: Yahoo! Finance
in its REVOLUTION clinical program, specifically regarding VYD2311, a monoclonal antibody candidate for COVID-19 prevention. A pre-specified analysis of the Phase 3 DECLARATION study revealed that accumulated clinical events already provide sufficient statistical power to support high-end efficacy targets. Consequently, Invivyd has triggered a conservative upsizing of the study by ~500 subjects to ensure robust data across various scenarios. This adjustment is expected to shift the timing of top-line results slightly, moving from mid-year guidance to Q3 2026. In addition to its COVID-19 efforts, the company revealed the discovery and advancement of VMS063, a novel monoclonal antibody for the treatment and prevention of measles. Designed to be a first-in-class precision therapy, VMS063 targets the measles Fusion protein to prevent cell entry, demonstrating high potency against circulating lineages in laboratory assays. With US measles incidence reaching decade-high levels, Invivyd Show less Read more
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