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Jade Biosciences Touts “Best-in-Class” Autoimmune Antibodies, JADE101 Phase 1 Readout Nears [Yahoo! Finance]

Jade Biosciences, Inc. (JBIO) 
Company Research Source: Yahoo! Finance
JADE101 (anti-APRIL) : A Phase 1 healthy-volunteer readout is expected in the first half of the year, and Jade says JADE101 is a femtomolar APRIL binder (claimed 750x potency vs. sibeprenlimab) with a YTE half-life extension aiming for subcutaneous dosing no more frequent than every eight weeks to drive deep, durable APRIL/IgA reductions. JADE201 (anti-BAFF-R) : First-in-human dosing is planned in Q2 in rheumatoid arthritis (as a surrogate for healthy-volunteer testing) with data expected in 2027; the program is designed to mimic ianalumab pharmacology but add half-life extension and will be evaluated across many potential indications where B-cell depletion is used. Financial runway : Jade ended 2025 with $336 million in cash, which management says should fund the company into the first half of 2028 and cover the near-term clinical milestones. Interested in Jade Biosciences, Inc.? Here are five stocks we like better. Jade Biosciences (NASDAQ:JBIO) outlined its strategy and ne Show less Read more
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