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Stock impact report

MSD-backed Ray locks in $125m to back eye drug pipeline [Yahoo! Finance]

Janus Henderson Group plc Ordinary Shares (JHG) 
Last janus henderson group plc ordinary shares earnings: 4/30 04:00 am Check Earnings Report
US:NYSE Investor Relations: snl.com/irw/corporateprofile/4147331
Company Research Source: Yahoo! Finance
Through the oversubscribed round, which was led by Janus Henderson Investors and featured contributions from MSD's (Merck & Co) venture arm, MRL Ventures Fund and Novo Holdings, Ray will fund the late-stage clinical development and commercial readiness of RTX-015. Ray is currently evaluating RTX-015 through the Phase I ENVISION study (NCT06460844), which is looking at the drug's potential in patients with retinitis pigmentosa (RP), a genetic disease which causes the light-sensitive cells in the retina to break down. RTX-015 acts by delivering a light-sensitive receptor protein called a rhodopsin to surviving retinal neurons, which then repurpose into light-sensitive photoreceptors – thus effectively replacing photoreceptors lost in the eye, regardless of genetic mutations. This differs from the approach harnessed by Spark Therapeutics' and Novartis' approved RP medicine, Luxturna (voretigene neparvovec), which delivers a copy of the RPE65 gene to restore the RPE65 enzyme's func Show less Read more
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