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-0.00131847847583881 -0.00336212011338909 -0.00336212011338909 -0.000593315314127519 0.000725163161711475 -0.00131847847583881 0.000758125123607417 -0.0138769859582042
Stock impact report

Janssen-Cilag seeks expanded EMA approval for TREMFYA [Yahoo! Finance]

Johnson & Johnson (JNJ) 
Last johnson & johnson earnings: 4/14 06:31 am Check Earnings Report
US:NYSE Investor Relations: jnj.com
Company Research Source: Yahoo! Finance
authorisation application for TREMFYA (guselkumab) to treat adults with active ulcerative colitis and Crohn's disease. The applications are based on positive results from the randomised, double-blind, placebo-controlled, multicentre Phase III QUASAR and GALAXI clinical trial programmes in ulcerative colitis and Crohn's disease respectively. The two trials assessed the safety and efficacy of guselkumab in adult patients with moderately to severely active ulcerative colitis or with Crohn's who showed an inadequate response to or intolerance of standard treatment. Guselkumab met the primary endpoint and offered improvements over placebo in symptoms and disease activity measures Its safety profile was in line with the previous findings of the therapy in approved indications. Data from the Phase III GALAXI 2 and 3 studies showed that guselkumab met the co-primary endpoints at week 12. Treatment with guselkumab also offered statistically significant and clinically meaningful imp Show less Read more
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