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Stock impact report

Kodiak Sciences dosing subjects in Phase III trial of diabetic retinopathy drug [Yahoo! Finance]

Kodiak Sciences Inc (KOD) 
Last kodiak sciences inc earnings: 11/12 05:30 am Check Earnings Report
Company Research Source: Yahoo! Finance
The randomised, multi-centre trial will assess the efficacy and safety of tarcocimab tedromer in treatment-naïve DR patients. Patients are being randomised at a 1:1 ratio to receive intravitreal injections of tarcocimab tedromer at baseline, week four, week eight, week 20 and week 44. The proportion of eyes showing an improvement of at least two steps on the Diabetic Retinopathy Severity Scale (DRSS) from baseline at week 48 is the trial's primary endpoint. Further outcome measures will assess the proportion of eyes that develop sight-threatening complications of DR and the proportion of eyes improving by three or more steps on the DRSS from baseline at week 48. Kodiak Sciences aims to finish enrolling subjects in the study by the end of this year. If successful, the trial could help the company secure a marketing authorisation application for tarcocimab tedromer. The GLOW2 trial's study design is similar to that of the previous GLOW1 study, which found an 89% reduction i Show less Read more
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