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Pasithea Therapeutics Announces the First Cohort has Completed the Initial Dosing in its Phase 1 Trial Evaluating PAS-004 in RAS, NF1 and RAF Mutated Cancers [Yahoo! Finance]

Pasithea Therapeutics Corp. (KTTA) 
Company Research Source: Yahoo! Finance
SOUTH SAN FRANCISCO, Calif. and MIAMI, Fla., April 24, 2024 (GLOBE NEWSWIRE) -- Pasithea Therapeutics Corp. (NASDAQ: KTTA) (“Pasithea” or the “Company”), a clinical-stage biotechnology company developing PAS-004, a next-generation macrocyclic MEK inhibitor for the treatment of neurofibromatosis type 1 (NF1) and other indications, today announced the first cohort of 3 patients have commenced dosing. PAS-004 is being evaluated in a Phase 1 multicenter open label clinical trial ( NCT06299839 ) in patients with MAPK pathway driven advanced solid tumors with a documented RAS, NF1 or RAF mutation or patients who have failed BRAF/MEK inhibition. “Completion of the initial dosing of the first cohort of 3 subjects is a significant milestone in Pasithea's mission towards developing PAS-004 as a potential best-in-class next-generation MEK inhibitor. This Phase 1 study is designed to provide key insights into the safety, tolerability, pharmacokinetics and pERK biomarker data and we look forwar Show less Read more
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