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Stock impact report

KYMR Initiates Dosing in Mid-Stage Asthma Study of Lead Candidate [Yahoo! Finance]

Kymera Therapeutics, Inc. (KYMR) 
Company Research Source: Yahoo! Finance
KT-621 is an investigational, first-in-class, once-daily, oral degrader of STAT6, the specific transcription factor responsible for IL-4/IL-13 signaling and the central driver of type II inflammation. KYMR expects to report top-line data from the BREADTH study in late 2027. Asthma is a chronic inflammatory lung disease that restricts airways and impairs breathing. Currently available medicines include inhalers and injectable biologics. However, there remains a significant unmet need for an improved treatment option. Kymera Therapeutics highlighted the medical risks associated with uncontrolled asthma and the ongoing lack of sufficiently effective treatment options, underscoring the need for new therapies. The initiation of patient dosing in the BREADTH study represents a key development step for KT-621 as a potential oral treatment for chronic type II inflammatory diseases, aligning with the company's strategy to develop convenient, biologics-like oral medicines for conditions wit Show less Read more
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