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0.00694228817284899 0.010889361602098 0.0202746250894232 0.00669669249280678 -0.06739426141134 -0.0421768478355827 -0.0241957355467818 -0.0207310822033299
Stock impact report

Kyverna to seek first clearance of a CAR-T therapy for autoimmune disease [Yahoo! Finance]

Kyverna Therapeutics, Inc. (KYTX) 
Company Research Source: Yahoo! Finance
Kyverna Therapeutics will seek clearance of what could be the first marketed cell therapy for an autoimmune condition after the treatment succeeded in a pivotal trial in a progressive condition known as stiff person syndrome. According to Kyverna, four months after treatment with its therapy miv-cel, Phase 2 study participants had a median 46% improvement from the trial's start on a type of timed walking test. More than four-fifths had at least a 20% improvement, a threshold that's believed to be “clinically meaningful,” Kyverna said Monday. The therapy met its key secondary study goals as well. Kyverna said there were no “high-grade” cases of the immune or neurological side effects associated with treatments like miv-cel. There were Grade 3 or 4 instances of neutropenia, or low counts of a kind of white blood cell, but Kyverna said they were “manageable.” Kyverna will seek U.S. approval in the first half of next year. Kyverna has long been a front-runner in the race to transfo Show less Read more
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