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Stock impact report

Kazia concludes first stage of Phase I advanced cancer treatment trial [Yahoo! Finance]

Kazia Therapeutics Limited - American Depositary Shares (KZIA) 
US:NASDAQ Investor Relations: kaziatherapeutics.com
Company Research Source: Yahoo! Finance
The trial's Safety Review Team (SRT) has confirmed that the study has met its primary and secondary objectives for this stage. The dose-finding, open-label study is focused on evaluating the safety, tolerability, and pharmacokinetics (PK) of EVT801 in subjects with advanced or metastatic solid tumours who are not responsive to standard treatment or for whom no standard therapy is available. It enrolled patients with eleven different types of advanced or metastatic solid tumours, including ovarian cancer, which was the most prevalent among the participants. The primary objective of the trial was to assess the safety and tolerability of EVT801 as well as to establish the maximal tolerated dose (MTD) and / or a recommended Phase II dose (RP2D) of EVT801 daily dose. Secondary objectives included characterising the PK profile of the oral capsule formulation of EVT80, identifying active metabolites of EVT801 in plasma, and detecting initial anti-tumour activity. To validate the t Show less Read more
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