Kazia Therapeutics Reports Early Conclusion of Clinical Trial After Reaching Primary Endpoint [Yahoo! Finance]
Kazia Therapeutics Limited - American Depositary Shares (KZIA)
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kaziatherapeutics.com
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Source: Yahoo! Finance
SYDNEY Feb. 21, 2024 /PRNewswire/ -- Kazia Therapeutics Limited (NASDAQ: KZIA), a biotechnology company specializing in oncology, today announced the early conclusion based on positive safety and promising clinical response findings observed to date of an important two-part Phase I trial. This investigator-initiated trial evaluated the use of paxalisib (an oral PI3K/mTOR dual inhibitor) with radiation therapy for the treatment of patients with PI3K pathway mutation brain metastases from solid tumors. Part I of the study established the maximal tolerated dose (MTD) of paxalisib in combination with radiation therapy, while also demonstrating promising signs of clinical activity in all nine evaluable patients. Part II was a follow-on expansion cohort to further evaluate safety and efficacy of the MTD (45mg daily) combined with radiation therapy in up to 12 additional patients. After reviewing the Part II patient data generated to date, the three lead investigators have determined th
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News
- Kazia Therapeutics licenses paxalisib to Sovargen for intractable seizures in rare central nervous system diseases [Yahoo! Finance]Yahoo! Finance
- Kazia Therapeutics licenses paxalisib to Sovargen for intractable seizures in rare central nervous system diseasesPR Newswire
- Kazia announces presentation of new data at AACR Annual Meeting [Yahoo! Finance]Yahoo! Finance
- Kazia announces presentation of new data at AACR Annual MeetingPR Newswire
- Kazia Therapeutics Reports Early Conclusion of Clinical Trial After Reaching Primary EndpointPR Newswire
KZIA
Sec Filings
- 4/19/24 - Form 424B3
- 4/19/24 - Form 6-K
- 3/27/24 - Form 424B3
- KZIA's page on the SEC website