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Stock impact report

New positive data from phase IIa trial in brain cancer patients

Kazia Therapeutics Limited - American Depositary Shares (KZIA) 
US:NASDAQ Investor Relations: kaziatherapeutics.com
Company Research Source: PR Newswire
SYDNEY, May 8, 2019 /PRNewswire/ -- With one month to go until World Brain Tumour Day on June 8, Kazia Therapeutics Limited (ASX: KZA; NASDAQ: KZIA), an Australian oncology-focused biotechnology company, is pleased to announce new safety data from its ongoing phase IIa study of GDC-0084 in newly-diagnosed patients with glioblastoma (GBM). Experience the interactive Multichannel News Release here: https://www.multivu.com/players/English/8542751-kazia-therapeutics-glioblastoma/ Licensed from Genentech in October 2016, GDC-0084 is a novel targeted therapy that inhibits the PI3K pathway, which is important in many forms of cancer and is activated in 85-90% of GBM cases. GDC-0084 is administered orally, once daily. The phase II a study has determined a maximum tolerated dose (MTD) of 60mg, which is substantially higher than the 45mg dose found during Genentech's phase I study in patients with recurrent disease. Dose-limiting toxicities in this phase II a study included oral mucositis (mou Show less Read more
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