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Eli Lilly's Next-Generation Obesity Drug Secures First Phase III Win [Yahoo! Finance]

Eli Lilly and Company (LLY) 
Last eli lilly and company earnings: 4/23 06:25 am Check Earnings Report
US:NYSE Investor Relations: investor.lilly.com
Company Research Source: Yahoo! Finance
This study, called TRIUMPH-4, evaluated two doses (9 mg and 12 mg) of the drug for 68 weeks against placebo in adults with obesity or overweight and knee osteoarthritis (OA), and without diabetes. Ei Lilly reported results using two approaches — an efficacy estimand, which reflects outcomes in patients who stayed on treatment throughout the study period, and a treatment-regimen estimand, which incorporates data from patients who discontinued treatment. Under the efficacy estimand, Eli Lilly reported that patients on the 12 mg dose lost an average of 28.7% of their body weight, while those on the 9 mg dose lost 26.4%. In comparison, patients on placebo lost 2.1% of their body weight. For the other co-primary endpoint of improvement in knee pain, retatrutide achieved a reduction of 74-76% across both doses compared with the 40.3% reported in the placebo group. Concerning the treatment-regimen estimand, patients on the 12 mg dose lost an average of 23.7% of their body weight while t Show less Read more
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