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-0.0183595612780163 0.0336194563662375 0.0522174535050071 0.097520267048164 0.0865522174535049 0.0116833571769192 0.00548402479732931 -0.0100143061516454
Stock impact report

Leap Therapeutics Reports Updated Clinical Data from Sirexatamab Colorectal Cancer Study and Announces Exploration of Strategic Alternatives [Yahoo! Finance]

Leap Therapeutics, Inc. (LPTX) 
Last leap therapeutics, inc. earnings: 11/14 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: investors.leaptx.com
Company Research Source: Yahoo! Finance
Board of Directors has initiated process to explore strategic alternatives to maximize shareholder value CAMBRIDGE, Mass. June 23, 2025 /PRNewswire/ -- Leap Therapeutics, Inc. (Nasdaq:LPTX), a biotechnology company focused on developing targeted and immuno-oncology therapeutics, today reported updated results from Part B of the DeFianCe study ( NCT05480306 ), a Phase 2 study of sirexatamab (DKN-01), an anti- DKK1 monoclonal antibody, in combination with bevacizumab and chemotherapy (Sirexatamab Arm) compared to bevacizumab and chemotherapy (Control Arm) in patients with advanced microsatellite stable (MSS) colorectal cancer (CRC) who have received one prior systemic therapy for advanced disease. Due to the Company's financial position, Leap's Board of Directors is taking further steps to preserve capital and has initiated a process to explore strategic options to preserve and maximize shareholder value. "Sirexatamab demonstrated a statistically significant benefit in patients wit Show less Read more
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