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0.0456852791878173 0.0558375634517767 0.0710659898477157 0.0558375634517767 0.0710659898477157 0.248883248730965 0.142182741116751 0.248730964467005
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LAVA Therapeutics Announces Collaboration with Merck & Co., Inc., Rahway, NJ, USA to Evaluate LAVA-1207 in Combination with KEYTRUDA® [Yahoo! Finance]

LAVA Therapeutics N.V. - Ordinary Shares (LVTX) 
Company Research Source: Yahoo! Finance
Enrollment will continue in the monotherapy and IL-2 combination arms of the study LAVA Therapeutics N.V. Nasdaq: LVTX ), today announced that it has entered into a clinical trial collaboration and supply agreement with Merck & Co., Inc., Rahway, NJ, USA to evaluate its anti-PD-1 therapy KEYTRUDA® (pembrolizumab) in combination with LAVA-1207, a Gammabody ® designed to target the prostate-specific membrane antigen (PSMA) to trigger the potent and preferential killing of PSMA-positive tumor cells, in patients with therapy refractory metastatic castration-resistant prostate cancer (mCRPC). Under the terms of the agreement, Merck & Co., Inc., Rahway, NJ, USA will provide pembrolizumab for the dose escalation and expansion phases of LAVA's ongoing Phase 1/2a study of LAVA-1207 ( NCT05369000 ), with the combination arm expected to be initiated in the first half of 2024. Enrollment and dose escalation will also continue in the LAVA-1207 monotherapy and interleukin-2 arms of the study. Show less Read more
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