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0 -0.00306748466257665 -0.00306748466257665 0.00626833822352623 0.0156041611096292 0.0322752734062417 0.0189383835689518 0.0216057615364098
Stock impact report

H.C. Wainwright Says Market Remains Unconvinced on Lexeo Therapeutics, Inc. (LXEO)'s PKP2 Program [Yahoo! Finance]

Lexeo Therapeutics, Inc. (LXEO) 
Company Research Source: Yahoo! Finance
TheFly reported on January 13 that H.C. Wainwright analyst Mitchell Kapoor lowered the price target for LXEO to $10 from $13 and maintained a Buy rating. The firm believes that the market is still not persuaded by LXEO's recent PKP2 findings; the drop implies a lesser possibility of acceptance for the PKP2 program. A day earlier, on January 12, Lexeo Therapeutics, Inc. (NASDAQ:LXEO) released preliminary results from its HEROIC-PKP2 Phase I/II trial of LX2020, which is an AAV-based gene therapy for PKP2-associated arrhythmogenic cardiomyopathy. There was no clinically significant complement activation, and LX2020 was usually well tolerated across dosage cohorts. PKP2 protein increased in a dose-dependent manner during treatment, averaging 93% in the low-dose group and 162% in the high-dose group. Premature ventricular contractions and non-sustained ventricular tachycardia are examples of arrhythmia features that often improve or stabilize. Lexeo Therapeutics, Inc. (NASDAQ:LXEO) is Show less Read more
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