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Stock impact report

Lyell Immunopharma Reports Business Highlights and Financial Results for the Third Quarter 2025 

Lyell Immunopharma, Inc. (LYEL) 
Company Research Source: GlobeNewswire
Acquired exclusive global rights to LYL273, a novel GCC-targeted CAR T-cell product candidate that has demonstrated a 67% overall response rate, an 83% disease control rate and a manageable safety profile at the highest dose level studied to date in patients with refractory metastatic colorectal cancer in an ongoing U.S. Phase 1 clinical trialReceived RMAT designation from the U.S. FDA for ronde-cel for the treatment of patients with relapsed or refractory LBCL receiving treatment in the second-line (2L) settingAnnounced that two abstracts highlighting new clinical and translational data from the Phase 1/2 clinical trial of ronde-cel for the treatment of aggressive large B-cell lymphoma have been accepted for oral presentation at the ASH 67th Annual Meeting and Exposition in DecemberAnnounced the initiation of PiNACLE - H2H, a Phase 3 head-to-head CAR T-cell therapy clinical trial in aggressive large B-cell lymphoma in the 2L settingFormed a PiNACLE – H2H Steering Committee comprised Show less Read more
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