Mateon to Develop its OT-101, a Phase 3 Clinical Drug Candidate, Initially Against COVID-19
MATEON THERAPEUTICS (MATN)
Last mateon therapeutics earnings: 11/19 05:25 pm
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Source: GlobeNewswire
OT-101- a TGF-ß2 inhibitor - has demonstrated potent antiviral activity against coronavirus OT-101 - an RNA therapeutic - is part of the Company’s proprietary platform for rapid antiviral response AGOURA HILLS, Calif., March 18, 2020 (GLOBE NEWSWIRE) -- Mateon Therapeutics, Inc. (OTCQB:MATN) (“Mateon”) dedicated to development OT-101, a TGF-Beta antisense drug candidate, today provided an update on its rapid antiviral response program against coronaviruses, with a target of the coronavirus, initially the COVID-19 virus. Mateon has made significant progress in deploying its phase 3 clinical asset, OT-101, against coronavirus. In an in vitro antiviral testing performed by an independent laboratory, OT-101 has an 50% effective concentration (EC50) of 7.6 µg/mL and is not toxic at the highest dose of 1000 µg/mL giving a safety index (SI) value of 130, which is considered highly active. Mateon intends to work with the Food and Drug Administration (FDA) to permit OT-101 to en
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