Moleculin announces efficacy results from trial of Annamycin for STS lung mets [Yahoo! Finance]
Moleculin Biotech, Inc. (MBRX)
Last moleculin biotech, inc. earnings: 8/16 05:35 pm
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Source: Yahoo! Finance
The Phase IB in this open-label, multi-centre trial aims to determine the maximum tolerable dose and recommended Phase II dose, as well as assess the safety. Phase II focused on the efficacy of Annamycin as a monotherapy. The clinical benefit rate was 59.4%, with one participant achieving a partial response and 18 showing stable disease. Dose and regimen-optimised participants showed progression-free survival (PFS) and an overall survival (OS) of around four and 20 months, respectively. The median PFS was 63 days, and the median OS was 411 days for all participants. In Phase II, at a dose of 330 mg/m², the median PFS was 105 days, with an OS of 13.5 months for those who had undergone a median of six previous therapies, exceeding typical outcomes for second-line monotherapies. Participants with fewer previous therapies and receiving the recommended Phase II dose showed even better outcomes, with an OS and PFS of 19.9 months and 127 days, respectively. The study also highli
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- Moleculin Biotech (NASDAQ:MBRX) had its "buy" rating reaffirmed by analysts at Roth Capital.MarketBeat
- Moleculin Biotech (NASDAQ:MBRX) had its "buy" rating reaffirmed by analysts at HC Wainwright.MarketBeat
- Moleculin Announces Exercise of Warrants for $6.8 Million Gross ProceedsGlobeNewswire
- Moleculin Announces Completion of Treatment for the 45 Patients in Pivotal “MIRACLE” Phase 3 AML Trial on Pace for Q1 2026GlobeNewswire
MBRX
Sec Filings
- 12/23/25 - Form S-3
- 12/23/25 - Form 424B5
- 12/22/25 - Form PRER14A
- MBRX's page on the SEC website