PatentVest Releases New Report on The Oral Small-Molecule GLP-1 Patent Race
MDB Capital Holdings, LLC - Class A common (MDBH)
Company Research
Source: GlobeNewswire
Dallas, TX, Feb. 26, 2026 (GLOBE NEWSWIRE) -- PatentVest, the first fully integrated IP intelligence and strategy firm, has released its latest PatentVest Pulse report, “The Oral Small-Molecule GLP-1 Race: Beyond Orforglipron.” As injectable GLP-1 drugs built a $71 billion market while reaching less than 5% of eligible patients, fifty oral small-molecule programs are now racing to unlock the remaining 95%. Clinical efficacy across leading programs is converging in the 12–16% weight-loss range. In this increasingly competitive field, long-term differentiation depends not only on clinical performance but also on the strength and defensibility of each program’s patent portfolio. The report reviews more than 1,200 patent documents across 26 clinical-stage programs, mapping composition-of-matter claims, Markush scope, formulation layers, and method-of-use protection. The findings reveal dramatic disparities in patent depth between programs at similar development stages. More than $47
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